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DNA race to unlock ageing secrets

Posted: Published on July 24th, 2012

24 July 2012 Last updated at 02:28 ET By Helen Briggs BBC News A race to unlock genetic clues behind living to 100 is set to begin next year, after a US team announced it will compete for the $10m Genomics X Prize. Genetic entrepreneur Dr Jonathan Rothberg is entering the challenge to identify genes linked to a long, healthy life. His team - and any other contenders - will be given 30 days to work out the full DNA code of 100 centenarians at a cost of no more than $1,000 per genome. The race will start in September 2013. Under the rules of the Archon Genomics X Prize, teams have until next May to register for the competition. Dr Rothberg's team from Life Technologies Corporation in California is the first to formally enter the race. Being able to sequence the full human genome at a cost of $1,000 or less is regarded as a milestone in science. It is seen as the threshold at which DNA sequencing technology becomes cheap enough to be used widely in medicine, helping in diagnosis and in matching drugs to a patient's genetic make-up. If they can do a human genome in two … Continue reading →

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Osiris Therapeutics Announces Second Quarter 2012 Financial Results Conference Call

Posted: Published on July 24th, 2012

COLUMBIA, Md.--(BUSINESS WIRE)-- Osiris Therapeutics, Inc. (OSIR) today announced that it will report its financial results for the second quarter ended June 30, 2012, on Monday, July 30, 2012. C. Randal Mills, Ph.D., President and Chief Executive Officer, and Philip R. Jacoby, Jr., Chief Financial Officer, will provide a company update and discuss results via a webcast and conference call on Monday, July 30, 2012 at 9:00 a.m. ET. To access the webcast, visit the Investor Relations section of the company's website at http://investor.osiris.com/events.cfm. Alternatively, callers may participate in the conference call by dialing (877) 303-6133 (U.S. participants) or (970) 315-0493 (international participants). A replay of the conference call will be available approximately two hours after the completion of the call through August 05, 2012. Callers can access the replay by dialing (855) 859-2056 (U.S. participants) or (404) 537-3406 (international participants). The audio replay passcode is 99408506. To access a replay of the webcast, visit the Investor Relations section of the company's website at http://investor.osiris.com/events.cfm. About Osiris Therapeutics Osiris Therapeutics, Inc. is the leading stem cell company, having developed the worlds first approved stem cell drug, Prochymal. The company is focused on developing and marketing products to treat medical conditions … Continue reading →

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Not having child does not prove impotency: High Court

Posted: Published on July 24th, 2012

Observing that there is a marked difference between 'infertility' and 'impotency', Bombay High Court today set aside a 1994 order of divorce. The family court, in October 1994, had granted divorce to the husband (then 42 years old) on the ground that the wife (then 45 years old) was impotent, a valid ground for divorce as contemplated by Section 12 (1) (a) of Hindu Marriage Act. The wife challenged the divorce order in High Court. The division bench of Justices A M Khanwilkar and A R Joshi today set aside the divorce, observing that family court had erred in equating infertility with impotency. "The family court held that inability to give birth to a child presupposed that woman is impotent. This view taken by the family court is erroneous and it is wrong in accepting infertility of a woman equivalent to her impotency," the bench said. The family court had said that even after 16 years of marriage, there was no child, which was sufficient to establish that wife was impotent. "We must say that the family court has definitely committed an error in arriving at such a conclusion and treating impotency and infertility at par. There is a marked … Continue reading →

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UPDATE 2-U.S. FDA OKs Forest/Almirall drug for smoker's cough

Posted: Published on July 24th, 2012

(Adds background on Forest, drug side effects, competitors, shares) WASHINGTON, July 23 (Reuters) - Forest Laboratories Inc's inhaled treatment for smoker's cough, commonly called COPD and the fourth leading killer in America, has been approved by U.S. drug regulators, bolstering the company's plans to grow profits through new medicines. The U.S. Food and Drug Administration approved the twice-daily drug, to be sold as Tudorza Pressair, to treat symptoms of chronic obstructive pulmonary disease (COPD), a serious lung disease that makes breathing difficult and is often caused by cigarette smoking. Forest developed the drug, which loosens the muscles around the lungs to improve airflow, with Spanish company Almirall SA and will market it in the United States. "The availability of long-term maintenance drugs for COPD provides additional treatment options for the millions of people who suffer with this debilitating disease," said Dr. Curtis Rosebraugh, director of the FDA's Office of Drug Evaluation II. About 14 million people in the United States and 64 million worldwide have COPD, which worsens with age and can persist even if smokers with the disease quit the habit. The FDA was originally supposed to decide on the drug by April 23, but delayed the decision to … Continue reading →

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Reformulated Oxycontin Leads Drug Abusers To Opana

Posted: Published on July 24th, 2012

(credit: Darren McCollester/Getty Images) By John Ostapkovich PHILADELPHIA (CBS) Law enforcement agencies are on alert for people who are willing to acquire a powerful painkiller called Opana at point of gun. Opana is on opioid, like Oxycontin, says Pharmacy Doctor Bruce Canaday, department chair at the University of the Sciences in Philadelphia, and it has gained traction among drug abusers. One reason, Canaday says, is the drug Oxycontin, once highly-valued by junkies, has changed. Not too long ago, they reformulated their product so that now if you try to open it up or crush it or mix it with water, it turns to a viscous jelly-like substance which is very hard to snort of shoot. And, that has drug abusers looking for Opana. There was a relatively rapid wholesale shift in drug abuse from that product which was very difficult to abuse now to the Opana, which was not now not difficult to abuse, and its also much more dangerous, because its much more potent than Oxycontin was, so 40 mg of one doesnt equal 40 mg of the other. The maker of Opana has also reformulated the pill to deter abuse, and there have been pharmacy stickups in the … Continue reading →

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Australian drug mule gets 8 years in Bali jail

Posted: Published on July 24th, 2012

Indonesian prosecutors may appeal the sentence given to an Australian drug mule jailed for attempting to smuggle hashish and methamphetamines into Bali hidden in his stomach. Edward Myatt was jailed for eight years on Monday in a ruling that shocked prosecutors, who had demanded a sentence of 15 years. The 54-year-old Ballarat-born man was also fined 1.5 billion rupiah ($A155,000). If he fails to pay the fine, Myatt will be required to serve an additional four months in jail. The decision is another major relief for Myatt, who was indicted on three charges, including one count of trafficking, which carries a maximum penalty of death. He was stopped as he arrived at Bali's Ngurah Rai Airport in February on a flight from India after he aroused the suspicions of Customs officers. He was later found to have swallowed more than 70 plastic casings containing 1.1kg of hashish and four grams of methamphetamine, otherwise known as ice. It had been expected he would receive a similar sentence to Sydney-man Michael Sacatides, who earlier this year was given 18 years for attempting to smuggle 1.7kg of ice into Bali from Thailand. But chief judge Gunawan Tri Budiono said that while the evidence … Continue reading →

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Many Medicaid Patients Skip Drugs That Could Prevent Heart Trouble

Posted: Published on July 24th, 2012

FRIDAY, July 20 (HealthDay News) -- Many Medicaid recipients with chronic health conditions that can lead to heart disease -- diabetes, high blood pressure and high cholesterol -- do not take their prescribed medications, a new study has found. The researchers said failure to take medications leads to higher costs of care and an increased risk of hospitalization and even death. They looked at 2008 and 2009 data from more than 150,000 Medicaid patients in New York City, aged 20 to 64, and found that only 63 percent of those with the three chronic conditions took their prescribed medications. Older patients and white and Asian patients were most likely to take their medications, while black and Hispanic patients were least likely. "The outcome of this study is concerning, as it shows a large number of people with chronic conditions that lead to cardiovascular disease aren't taking prescribed medications, which could prevent a potential stroke or heart attack," lead author Dr. Kelly Kyanko, an instructor in the department of population health at the NYU Langone Medical Center, said in a center news release. "We hope these findings will help local health authorities in the New York City area address this problem … Continue reading →

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Drugs-for-bombs racket in Lampang

Posted: Published on July 24th, 2012

A racket involving the trading of drugs for stolen explosives is widespread in Lampang, according to a report released on Tuesday by Lampang provincial police, news reports said. Following the arrest of a suspect in Muang district, on Sept 19, police seized four kilogrammes of crystal methamphetamine, known asice, two sticks of dynamite and one "power gel" bomb from his residence. According to the police report, the suspect admitted to stealing theexplosives from lignite mines in Mae Mau district operated by the Electric Authority of Thailand, with the help of a company employee. The stolen explosives weretraded for drugs, he said. Thesuspect told police that he had no ideahow or where the explosiveswere used. Asource in a military unit in Lampang, who asked not to be named,was saidthe drugs-for-bombs racket is rampant inthe area, according to news reports. He saidsecurity officers in the area were worried that the bombs could get into the hands of terrorists. Thesource said Lampang,the country's main source of energy, isunder threat of daily bomb attacks, similar to the three southernmost provinces. You can introduce your kids to edutainment reading with our Student Weekly magazine: Thailand's only all-English entertainment and education magazine for teens and all … Continue reading →

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Missing meds force pharmacy to close

Posted: Published on July 24th, 2012

Chris Cole Pharmacy Closing Chris Cole Pharmacy has been a fixture in Arcadia for more than three decades, but in just a few days, the drug store will be history. "Our customers are very upset about the fact it's closing down," said owner Lee Brown. Brown says she has no choice but to close it down thanks to five women accused of stealing and selling more than 10-thousand pills. "They were waiting until the pharmacist went to sleep at night and going in and getting his key," said Bienville Parish Sheriff John Ballance. Investigators say the three main culprits are the pharmacist's step-daughter, Diana Lofton, and her daughters, Venus Lofton and India Feazel. Sheriff Ballance says the women also stole the pharmacist's code to the alarm system. Authorities say they broke into the pharmacy several times between June and July. The stolen pills were said to be sold for as much as ten dollars each in Bienville, Claiborne, Lincoln, Bossier and Caddo parishes. Also charged in connection are Christen Murphy and Alice Goodwin. Ballance says when Goodwin was arrested for an unrelated charge in Webster parish, she started singing like a bird. One month later, deputies had a flock of … Continue reading →

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Ryall ignores painful truth of pharmacy contract – Street

Posted: Published on July 24th, 2012

Pharmacists were left with no alternative but to sign-up to the new community pharmacy agreement and the Minister of Health is kidding himself if he thinks most did so happily. Labour's Health spokesperson, Maryan Street says pharmacists had no real choice but to cave in despite their concerns, because they would not have received payment for June if they did not. "Tony Ryall continues to ignore the pharmacists' concerns over gaps in the contract, such as how much they will get paid after 1 February next year, as well as their anxiety over patient safety and the viability of pharmacies in rural areas. "He has consistently treated the pharmacists with disdain even though many of them have taken their concerns directly to him. The Pharmacy Guild continues to tell the Minister that all is well when its own members are clear that the opposite is true," she says. "The change that this contract involves, and the haste with which it has been rushed through, threatens the livelihoods of many pharmacists and the care they can deliver as health professionals. If their pharmacies are not viable, that delivery of health care is threatened. "Mr Ryall should recognise when there is a … Continue reading →

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