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Research and Markets: Acute Spinal Cord Injury (ASCI) Therapeutics – Pipeline Assessment and Market Forecasts to 2019

Posted: Published on July 14th, 2012

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/4xw677/acute_spinal_cord) has announced the addition of GlobalData's new report "Acute Spinal Cord Injury (ASCI) Therapeutics - Pipeline Assessment and Market Forecasts to 2019" to their offering. Pharmaceutical Research into Spinal Cord Injuries Will Stretch into Next Decade Drugs under development to treat those affected by acute spinal cord injuries are not expected to emerge within the current decade, leaving the market largely open to new entrants, according to a new report issued by pharmaceuticals intelligence provider GlobalData. The new report* shows that there have been no treatment options approved for Acute Spinal Cord Injury (ASCI) by either the Food and Drug Administration (FDA) or the European Medicines Agency (EMA), so off-label generic drugs dominate the market. Spinal Cord Injury (SCI) refers to damage to the spinal cord which results in the loss of mobility and feeling. SCI usually occurs due to a sudden traumatic blow to the spine that fractures or dislocates vertebrae, caused by injuries involving the head, pelvic fractures, penetrating injuries close to the spine, or injuries caused by a fall from a significant height. The classification of SCI into acute and chronic phases is based on the period of time the patient … Continue reading →

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Columbia Asia launches Parkinson's clinic

Posted: Published on July 14th, 2012

Bangalore, July 13 : Healthcare major Columbia Asia Referral Hospital has launched its Parkinson's and Movement Disorder clinic in Yeshwanthpur town in Bangalore. The doctors at Columbia Asia Referral Hospital cited a case history that prompted them to launch the clinic. Hitesh Gupta (name changed) had regular tremors on the left side of his body. He was also suffering from slowness in body movement, postural issues and slowness in speech. Despite all medications, Gupta's case started deteriorating. The prolonged use of medications resulted in various other complications including frequent hallucination. It is when Gupta's family decided to approach the doctors at Columbia Asia Referral Hospital, Yeshwanthpur. A team of doctors led by Dr Guruprasad, Consultant, Neurologist defined the disease to Gupta's family and helped them overcome the phobia. Subsequently, a Deep Brain Stimulation (DBS), an advanced surgical procedure, was performed on Gupta. Today Gupta is leading a normal life and his medications have come down by 90 per cent, said doctors. "DBS surgeries and lesioning surgeries are done through a small hole drilled in the head. These are high precision surgeries guided by latest neuro-navigation techniques. Patient is awake during the surgery so as to enable us to assess the … Continue reading →

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Report: DoD does not know if PTSD programs work

Posted: Published on July 14th, 2012

http://www.navytimes.com/news/2012/07/military-report-dod-va-ptsd-programs-effectiveness-071312/ The Defense Department has a woeful lack of information on the effectiveness and related costs of its post-traumatic stress disorder treatment programs, despite having spent millions on various initiatives to address psychological health and traumatic brain injury, a panel of top scientists concluded in a report released Friday. In a review of DoD and Veterans Affairs Department PTSD treatments mandated by Congress in 2010, an Institute of Medicine panel found fewer than half of all service members and veterans who screen positive for the disorders symptoms 40 percent have received referrals for care, and of those, just 65 percent actually go on to get help. The group also concluded that DoD and VA should improve tracking of treatment and outcomes and institute research programs to evaluate the effectiveness of their programs. Treatment isnt reaching everyone who needs it, and the departments arent tracking which treatments are being used or evaluating how well they work in the long term, said committee chairman Sandro Galea, head of the epidemiology department at Columbia University. The withering report comes as DoD and VA grapple with rising mental health issues within their ranks, including suicide. Of the more than 2.6 million active-duty, National Guard … Continue reading →

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Instant brain injury detection could soon be reality

Posted: Published on July 14th, 2012

Instant brain injury detection could soon be reality Imagine a handheld tool that can detect almost instantly whether a person has suffered a concussion or a traumatic brain injury. Researchers at the University of Nebraska are helping make that life-saving device a reality. "This device would be relatively inexpensive and something you could easily take out onto a football field or anywhere you might have a brain injury taking place," said bioanalytical chemist David Hage. When the brain suffers trauma, it releases a protein into the blood stream. Hage has found a way to detect that protein in a single drop of blood. "By measuring how much of the protein is there, you will be able to get an idea how badly that brain injury occurred," Hage said. The immediate information comes from a device the size of a calculator, which can get people treatment quicker and possibly prevent more severe brain damage. "If a person has another concussion while the person is still recovering, the brain can swell and it can be a very catastrophic injury," said Dr. Travis Groft, director of neuropsychology at the Madonna Rehabilitation Hospital. The U.S. Department of Defense is helping fund the research, and … Continue reading →

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Reducing stress reduced MS development

Posted: Published on July 14th, 2012

CHICAGO, July 13 (UPI) -- Patients with multiple sclerosis who participated in a weekly stress management program developed fewer new brain lesions, U.S. researchers said. David Mohr, principal investigator of the study and professor of preventive medicine at Northwestern University Feinberg School of Medicine in Chicago, said brain lesions in MS often precede flare-ups of symptoms such as loss of vision or use of limbs or pain. "This is the first time counseling or psychotherapy has been shown to affect the development of new brain lesions," Mohr said in a statement. "In MS the prevention of new brain lesions is an important marker used to judge how effective medications are. The new finding is an important step and the strongest evidence we have to date that stress is involved in MS." In the national clinical trial, 121 patients were randomized to receive stress management therapy for MS or be in a control group. Those in the therapy group received 16 sessions over a 24-week period during which they were taught coping skills to enhance their ability to prevent stressful events from occurring and to improve their capacity to manage their responses to stressful events that did arise. They received a … Continue reading →

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Researchers Develop Alzheimer’s Timeline

Posted: Published on July 14th, 2012

July 13, 2012 Connie K. Ho for redOrbit.com Your Universe Online Scientists from the Washington University School of Medicine recently revealed that they have developed a timeline that shows early signs of Alzheimers, even with unseen progress. The team of researchers examined families who had a genetic risk of having the disease. The findings, which were published recently in the New England Journal of Medicine, show that signs of Alzheimers can appear up to 25 years before diagnosis of the disorder. This important research highlights that key changes in the brain, linked to the inherited form of Alzheimers disease, happen decades before symptoms show, which may have major implications for diagnosis and treatment in the future, commented Clive Ballard, director of research at the Alzheimers Society, in a article by the BBC. The study included 128 people from Australia, the United Kingdom, and the United States. Of all the participants, 50 percent had the possibility of inheriting one of three mutations that could lead to Alzheimers. These mutations were found in people who were in their 30s and 40s, and those who had the mutations would later develop Alzheimers. Researchers state that the findings are useful in understanding the patterns … Continue reading →

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Medistem Launches Critical Limb Ischemia Clinical Trial

Posted: Published on July 14th, 2012

SAN DIEGO, CA--(Marketwire -07/13/12)- Medistem Inc. (MEDS) and the Chinese Conglomerate, Shanghai Jia Fu Medical Apparatus Inc, announced today successful administration of Medistem's Endometrial Regenerative Cell (ERC) universal donor stem cell product in 2 patients with critical limb ischemia as part of a 15 patient study. The ERC dosing procedure, which involves a series of intramuscular injections in the ischemic limb, was successfully performed, without any treatment-associated adverse effects observed in either patient. "The ERC is unique amongst clinical grade stem cells in that the cell is derived from the endometrium (lining of the uterus). Every month new blood vessels are formed in the endometrium, which subsequently are sloughed off during menstruation. We believe the ERC plays a critical role in forming new blood vessels, which is supported by numerous experiments we have conducted," said Thomas Ichim, CEO of Medistem. "Since the biological role of the ERC is to produce new blood vessels, it is our desire to use these cells to produce new blood vessels in the legs of patients with critical limb ischemia." Critical limb ischemia is an advanced form of peripheral artery disease that causes approximately 150-200,000 amputations per year in the USA. Dr. Michael Murphy of … Continue reading →

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Use of drugs endangers horses and horse racing, senators are told

Posted: Published on July 13th, 2012

WASHINGTON National regulations are needed to stop the continued abuse of racehorses with painkillers and other drugs, experts and members of the horse racing industry told a Senate committee on Thursday. "The horse racing industry has demonstrated an inability or unwillingness to regulate itself," testified Sheila Lyons, director of the American College of Veterinary Sports Medicine and Rehabilitation, at a Senate Commerce, Science and Transportation committee hearing. The issue of drug use in horse racing has received renewed attention after an investigation by the New York Times that found trainers in the United States had been caught illegally drugging horses 3,800 times since 2009. Unlike other sports, horse racing lacks a commission that issues uniform rules. Although most states have banned steroids in horse racing, rules and enforcement that regulate other performance-enhancing drugs and therapeutic medications vary across states. Certain medications can legitimately help the healing process of ailing horses, but when they are used to "mask pain on an unsound horse so that he or she can race on the track, the drug becomes an abusive practice that puts the life of the horse and jockey at risk," said committee chairman John Rockefeller (D-W.Va). Other drugs, such as demorphine, … Continue reading →

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Pharmacy student ‘ends life’

Posted: Published on July 13th, 2012

A final year student of B. Pharmacy course, V. Renuka, 20, committed suicide by consuming poison in a private hostel at Ghatkesar on Thursday, the police said. The woman hailing from Vikarabad got married to a marketing executive, Hari Prasad, a year ago. She joined in a private hostel to complete her programme in Omega College at Ghatkesar and used to go to the house of in-laws at Kukatpally now and then. She looked dejected since she returned from the in-laws house two days ago but didnt disclose anything to her friends in hostel, the police said. On Thursday, she didnt go to college. An inmate of the hostel, Deepti, found her in an unconscious condition around noon and rushed her to a local hospital. She was later shifted to another corporate hospital where she died while undergoing treatment, Ghatkesar Inspector, G. Sreeram Kumar, said. Girl commits suicide Minutes after chided by father for securing less marks in weekly tests, an intermediate final year student, K. Priyanka, 16, ended her life by gulping pesticide in her house at Bokkoniguda in Ghatkesar on Thursday, the police said. The students father, K. Laxma Reddy, reprimanded her for failing to focus on studies … Continue reading →

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Customers grieve death of Norfolk pharmacy worker

Posted: Published on July 13th, 2012

By Patrick Wilson The Virginian-Pilot July 13, 2012 NORFOLK About half the customers at Atrium Pharmacy know Tom Florence is gone. The others find out in the store. Florence, 48, worked at the pharmacy, next to Bon Secours DePaul Medical Center, as a technician for 18 years. He died Saturday after he was hit by a van on his street, Cape View Avenue, in the Bayview neighborhood. A garbage truck was idling in the road while Florence chatted with one of the trash collectors. He then stepped into the van's path, police said. The driver of the van, who was going around the garbage truck, didn't see him. Florence was thrown 37 feet, according to court records. Florence was like a younger brother to Jay Levine, the manager of the pharmacy. "He was unique," Levine said. Florence liked to make an offer to nearly everyone, Levine said: "What can I do for you?" He seemed to gain inner strength from helping others, never looking for personal benefit. Angela Shalhoup, a longtime customer, said she loved Florence's funny, calm demeanor. See the article here: Customers grieve death of Norfolk pharmacy worker … Continue reading →

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