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Weekend Stroke Patients Fare Worse Than Weekday Ones

Posted: Published on July 11th, 2012

Editor's Choice Academic Journal Main Category: Stroke Also Included In: Neurology / Neuroscience Article Date: 10 Jul 2012 - 10:00 PDT Current ratings for: Weekend Stroke Patients Fare Worse Than Weekday Ones There is even a term for the apparent difference in a patient's chances of receiving full care during weekends; it is called the weekend effect. Lead author, William L. Palmer, MA, MSc, and team wrote that the weekend effect challenges the statement made by many regarding the equality of care patients receive when being hospitalized, irrespective of when this occurs. Palmer and team set out to find out whether a stroke patient's access to the hospital's best and safest stroke care varies depending on whether he/she was admitted on a weekday or weekend. They carried out a retrospective cohort study of 93,621 patients, in England, who had been hospitalized with stroke from 1st April, 2009 to the end of March, 2010. The team gathered data on which day patients were hospitalized and compared six indicators of stroke care, including hospital discharge, 30-day readmission rates, availability of brain scans, availability of clot treatments (thrombolysis), seven-day mortality, and complications. Of these 93,621 stroke patients, irrespective of day of admittance to … Continue reading

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Despite Benefit, Hospitals Not Always Alerted of Incoming Stroke Patients

Posted: Published on July 11th, 2012

Study Highlights: EMBARGOED UNTIL 3 pm CT/4 pm ET, Tuesday, July 10, 2012 DALLAS, July 10, 2012 (GLOBE NEWSWIRE) -- Treatment is delivered faster when emergency medical services (EMS) personnel notify hospitals a possible stroke patient is en route, yet pre-notification doesn't occur nearly one-third of the time. That's according to two separate Get With The Guidelines(R)-- Stroke program studies published in American Heart Association journals. The American Heart Association/American Stroke Association recommends EMS notify hospitals of incoming stroke patients to allow stroke teams to prepare for prompt evaluation and treatment. Quick response is vital for stroke patients, particularly those with ischemic stroke, when a clot cuts off the blood supply to a portion of the brain. Clot-busting drugs can only be given within a limited time -- three to 4.5 hours after the onset of symptoms. For both studies, researchers examined the records of 371,988 acute ischemic stroke patients transported by EMS to one of 1,585 hospitals participating in the Get With The Guidelines--Stroke quality improvement program between 2003 and 2011. Pre-notification of hospital by EMS resulted in faster diagnosis and treatment for stroke patients, according to the study published in Circulation: Cardiovascular Quality & Outcomes. Pre-notification was independently … Continue reading

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Advance notice to ERs helps treat stroke

Posted: Published on July 11th, 2012

LOS ANGELES, July 10 (UPI) -- Treatment is faster when paramedics tell hospitals a possible stroke patient is en route, but this doesn't occur one-third of the time, U.S. researchers say. The American Heart Association/American Stroke Association both recommend emergency medical services notify hospitals of incoming stroke patients because quick response is vital for stroke patients, particularly those with ischemic stroke, when a clot cuts off the blood supply to a portion of the brain. Clot-busting drugs can only be given within a limited time -- 3 to 4 1/2 hours after the onset of symptoms -- researchers said. The researchers examined the records of 371,988 acute ischemic stroke patients transported by EMS to one of 1,585 hospitals participating in the Get With The Guidelines -- Stroke quality improvement program from 2003 to 2011. Pre-notification occurred in 67 percent of patients in 2011, a modest increase from the 58 percent in 2003, the study said. Pre-notification was independently associated with better treatment times for faster imaging, treatment of clot-busting drug tPA within 60 minutes on arrival and more eligible patients treated with tPA. "Despite national guidelines recommending pre-notification by EMS for acute stroke patients, it's disappointing that there's been little … Continue reading

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World Premiere of "Janne's Next Step" on Los Angeles' KTTV on July 29

Posted: Published on July 11th, 2012

"Janne's Next Step" is a Unique Documentary that Chronicles a Man's Fight to Walk Again After a Devastating Spinal Cord Injury WASHINGTON, July 10, 2012 /PRNewswire-USNewswire/ -- "The basis of Locomotor Training is the discovery that the spinal cord has a complicated circuitry that can control locomotor," said Dr. V. Reggie Edgerton, Distinguished Professor of Integrative Biology and Physiology and of Neurology at UCLA. "Our research has proven that the spinal cord can actually re-learn how to walk after a spinal cord injury, without input from the brain." After Janne Kouri suffered a tragic diving accident that nearly cost him his life, he was told he would never walk again. He underwent an experimental activity-based rehabilitation treatment called Locomotor Training that was developed by Dr. Reggie Edgerton (UCLA) and Dr. Susan Harkema (University of Louisville) in partnership with the Christopher and Dana Reeve Foundation. Locomotor Training re-teaches the spinal cord how to control motor functions, like walking, through repetitive motion. It was developed and perfected with the help of lab animals and brave people, like Janne. After months of intensive training, Janne began to regain function in his feet, then in his legs, and today Janne can take steps with … Continue reading

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New treatment welcome news for Parkinson’s and stroke patients

Posted: Published on July 11th, 2012

New research developed by The University of Queensland is set to change the future treatment of speech problems associated with stroke and Parkinson's disease. The new treatment is promising news for people with speech and language disorders that result from diseases within the nervous system. Professor Bruce Murdoch of the Centre for Neurogenic Communication Disorders Research within UQ's School of Health and Rehabilitation Sciences said preliminary trials of the new treatment were positive in the effective treatment of these speech and language disorders. The research has found a new technology, transcranial magnetic stimulation (TMS), can be used to stimulate the brain with a series of magnetic pulses delivered by a stimulating coil held over selected areas of the head. Professor Murdoch said TMS featured a coil, shaped like a figure eight, that was held over the patient's head to switch on part of the brain in Parkinson's sufferers and switch off a different part in stroke victims. The non-invasive technology is proving very effective in treating long-term sufferers of stroke and Parkinson's disease, where traditional therapy approaches have proven ineffective, he said. The brain can heal itself much better than we thought it could. Based on these findings, TMS would … Continue reading

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Neonatal brain less permeable than adult's, post-stroke

Posted: Published on July 11th, 2012

SAN FRANCISCO The ability for substances to pass through the blood-brain barrier is increased after adult stroke, but not after neonatal stroke, according to a new study by UCSF that will be published today (July 10) in the Journal of Neuroscience. The novel findings may have major implications for drug development and the treatment of neonatal stroke, the researchers said. The blood-brain barrier is selectively permeable and blocks unwanted molecules from entering into the brain. The selectivity is achieved through fine coordination in function of many transporting systems in endothelial cells, which line the interior of blood vessels, and communication between endothelial cells and several types of cells in the brain. When blood flow in an artery to the brain is blocked by a blood clot, as occurs in arterial stroke, brain energy metabolism is compromised, and ion and other transporting systems malfunction, leading to blood-brain disruption. The new finding suggests, the researchers said, that drugs used to treat stroke need to be tailored to the specific makeup of the neonate blood-brain barrier. "How the blood-brain barrier responds to stroke in adults and neonates currently is poorly understood," said senior author Zinaida Vexler, Ph.D., director of research at the Neonatal … Continue reading

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Blood-Brain Barrier Less Permeable in Newborns than Adults after Acute Stroke

Posted: Published on July 11th, 2012

Results from UCSF Study Are Critical Step in Developing Treatments for Newborns Who Suffer Strokes Newswise The ability for substances to pass through the blood-brain barrier is increased after adult stroke, but not after neonatal stroke, according to a new study the UCSF that will be published July 11 in the Journal of Neuroscience. The novel findings may have major implications for drug development and the treatment of neonatal stroke, the researchers said. The blood-brain barrier is selectively permeable and blocks unwanted molecules from entering into the brain. The selectivity is achieved through fine coordination in function of many transporting systems in endothelial cells, which line the interior of blood vessels, and communication between endothelial cells and several types of cells in the brain. When blood flow in an artery to the brain is blocked by a blood clot, as occurs in arterial stroke, brain energy metabolism is compromised, and ion and other transporting systems malfunction, leading to blood-brain disruption. The new finding suggests, the researchers said, that drugs used to treat stroke need to be tailored to the specific makeup of the neonate blood-brain barrier. How the blood-brain barrier responds to stroke in adults and neonates currently is poorly … Continue reading

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Medical Groups Back Hormone Therapy

Posted: Published on July 11th, 2012

Although the risks of hormone replacement therapy (HRT) for women have been debated over the past decade, a coalition of 15 major medical groups have issued a statement saying that it is safe when its taken for a short time to fight symptoms of menopause. In a joint news release, three of the groups the North American Menopause Society, The Endocrine Society and the American Society for Reproductive Medicine said that the associations issued the statement because to reassure women and their providers that hormone therapy is acceptable and relatively safe for healthy, symptomatic, recently postmenopausal women. Over the last 10 years, there has been a complete abandonment of hormone therapy in some settings accompanied by reluctance to treat women who would benefit from relief of their symptoms. As a result, some women have sought unproven alternative therapies. The groups conclusion came in response to what it called the highly controversial Womens Health Initiative, which concluded that HRTs risks outweighed its benefits when taken to avoid chronic diseases. The joint statement issued this week dealt with the benefits of HRT when taken to avoid menopausal symptoms like painful intercourse and dry vagina. The results of the WHI and the conflicting … Continue reading

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Genetic Testing for Athletes

Posted: Published on July 11th, 2012

Some doctors are asking if athletes should be genetically tested to see if they are at a greater risk for developing Alzheimer's disease or dementia. Dr. Steven DeKosky is the dean of the University of Virginia School of Medicine. He says there is more evidence that suggests repeated head injuries can cause memory loss later in life, and genes could play a role in increasing the risk. According to Dr. DeKosky, there are ethical concerns about telling people what their genetic makeup is because it doesn't necessarily confirm they will develop memory loss diseases. "We have a difficult habit of thinking that if I have this particular variant of a gene that I'm going to get the disease and if I don't have it I'm not going to get the disease and they're not that predictive," Dr. DeKosky said. An informal poll taken of experts in Alzheimer's disease and traumatic brain injury revealed 45% thought it was too early to introduce genetic testing in schools, and that more information is needed to discuss how the genetic testing would be useful. There are more than five million Americans living with Alzheimer's disease. This year alone caring for those patients will cost … Continue reading

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Physicians need more education on personalized medicine

Posted: Published on July 11th, 2012

Consumers armed with genetic testing information from the likes of 23andMe and a whole host of gene testing companies are showing up at the emergency room or their primary care physicians looking for answers. The problem is that those physicians dont know enough about the emerging field of personalized medicine, said Dr. Jennifer Lowry a pediatrician at Childrens Mercy Hospital, Kansas City, Missouri. Lowry, who works at the hospitals Center for Personalized Medicine and Therapeutic Innovation was speaking at MedCity CONVERGE Conference, Tuesday, in Philadelphia. Personalized medicine may be routine at Mayo Clinic but when parents show up with their childs genetic test results in the doctors office, many physicians are asking what this all means, Lowry said. They are like Whaaaat? Later, in an interview Lowry said that personalized medicine was not even taught when she was in medical school and she had to learn it by herself. She and others on the panel which included James Burn, president and CEO of genetic testing firm AssureRx and Mike Scott, patient advocate, chairman of National Organization for Rare Disorders agreed that physician education was essential. Burns said that AssureRx is exploring ways to educate patients simultaneously with those in the … Continue reading

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