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Cops: Gunbattle ends 14-hour standoff in pharmacy

Posted: Published on June 13th, 2012

By NBC News and msnbc.com news services ALLIANCE, Neb. -- A 14-hour standoff with a gunman at a pharmacy ended withthe suspect's death, the Nebraska State Patrol said early Wednesday. The dead suspect was identifed by policeas 27-year-old Andres Gonzales, of Alliance. A police statement did notsay how Gonzales died. However,the death was confirmed following a gunbattle inside the pharmacy with Nebraska State Patrol SWAT team members. None of the SWAT officers was injured. Nebraska State Patrol Lt. Lance Rogers said earlier that the gunman was wanted in connection with the shooting and wounding of two city police officers and a state patrol officer. None of their injuries is life-threatening. The gunman also held a hostage for hours Tuesday in a western Nebraska drugstore. The hostage, identified Wednesday by Collins as pharmacy owner Charles Lierk, 62, of Alliance. Lierk managed to escape but was shot while getting away, Collins said. Lierk was taken to a local hospital where he was in stable condition, she said. Rogers also said police found a body Tuesday in a nearby home but declined to say whether it is related to the standoff. Police don't know how that person died, Rogers said. 'Best hometown in … Continue reading

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Gunman dies after 14-hour Neb. pharmacy standoff

Posted: Published on June 13th, 2012

OMAHA, Neb. (AP) -- A gunman who held a pharmacy owner hostage at his store in rural western Nebraska is dead after a 14-hour standoff, the Nebraska State Patrol said early Wednesday. The gunman, 27-year-old Andres Gonzales, died after a shoot-out with Nebraska State Patrol SWAT team members at the pharmacy in Alliance, patrol spokeswoman Deb Collins said in a statement. None of the SWAT officers were injured. Gonzales earlier shot two city police officers and a state patrol officer, but none of them suffered life-threatening injuries, Nebraska State Patrol Lt. Lance Rogers said. The statement did not explain how Gonzales, of Alliance, died. The standoff began Tuesday morning when Gonzales entered the Thiele Pharmacy & Gifts in downtown Alliance, a Nebraska Panhandle city of about 8,600 people. Authorities said police officers responded to reports of a robbery. Gonzales took the pharmacy's owner, 62-year-old Charles Lierk, hostage for hours, Collins said. Lierk managed to escape but was shot as he ran and is in stable condition, Collins said. Police and the state patrol did not say who shot Lierk. Ray Hielscher told the Lincoln Journal Star that he was watching the pharmacy from a Radio Shack across the street and … Continue reading

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Fresh, purified fat stem cells grow bone faster, better

Posted: Published on June 13th, 2012

LOS ANGELES UCLA stem cell scientists who purified a subset of stem cells from fat tissue and used the stem cells to grow bone discovered that the bone formed faster and was of higher quality than bone grown using traditional methods. The finding may one day eliminate the need for painful bone grafts that use material taken from patients during invasive procedures. Adipose, or fat, tissue is thought to be an ideal source of mesenchymal stem cells cells capable of developing into bone, cartilage, muscle and other tissues because such cells are plentiful in the tissue and easily obtained through procedures like liposuction, said Dr. Chia Soo, vice chair of research for the UCLA Division of Plastic and Reconstructive Surgery. Soo and Bruno Pault, the co-senior authors on the project, are members of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. Traditionally, cells taken from fat had to be cultured for weeks to isolate the stem cells which could become bone, and their expansion increases the risk of infection and genetic instability. A fresh, non-cultured cell composition called stromal vascular fraction (SVF) also is used to grow bone. However, SVF cells taken from … Continue reading

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Some Stem-Cells May Not Be The Answer For Heart Disease

Posted: Published on June 12th, 2012

June 12, 2012 The use of stem-cells building-block cells that are harvested from embryos or adults to treat heart disease could rely on faith as much as it does science, after billions of dollars in research has not produced the results that researchers have been looking for. Questions and concerns on the topic arose during the recent opening of the multi-million-dollar Scottish Center for Regenerative Medicine (SCRM) in Edinburgh, chaired by Sir Ian Wilmut, the renowned scientist whose Dolly the sheep clone in 1996, was a groundbreaking step in stem cell technology. During the opening ceremonies of the Center, Christine Mummery of the Leiden University Medical Center in the Netherlands discussed how a 2001 claim, based on mice experimentation, indicated that bone-marrow cells could mend heart damaged by coronary disease, caused a mad rush of people to the clinics looking for a cure-all. With nothing in the way of systematic research in animals, the first patients were being treated within a year, prematurely by Mummerys account. She argued that the paper that launched the mass stampede was completely wrong, and subsequent studies proved that. But despite the findings, the 2001 paper has never been withdrawn. Norwegian professor Harald Arnesen in … Continue reading

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Heart disease and stem-cell treatments: caught in a clinical stampede

Posted: Published on June 12th, 2012

A few years ago, concerns over these heart trials were voiced by a Norwegian professor, Harald Arnesen. He concluded in 2007 that they are not convincing and that one German team had achieved striking results only because the control group in its trial had done particularly badly. Prof Arnesen called for a moratorium on this kind of stem-cell therapy. That still did not deter the clinicians. This January, another trial funded by the EU was announced the largest of all, with 3,000 heart-attack patients recruited from across Europe. The idea behind the trials is straightforward. During a heart attack, a clogged blood vessel starves heart muscle of oxygen. Up to a billion heart muscle cells, called cardiomyocytes, can be damaged, and the body responds by replacing them with relatively inflexible scar tissue, which can lead to fatal heart failure. So why not implant stem cells that can grow into cardiomyocytes? Stem cells, of course, come in many kinds: the embryonic variety have the potential to turn into all 200 cell types in the body. Adult stem cells, harvested from the patient, have a more limited repertoire: bone marrow stem cells generate blood cells, for example. So to claim, as was … Continue reading

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Summit Corporation PLC: Summit achieves SMT C1100 Phase 1 dosing milestone that triggers milestone payment

Posted: Published on June 12th, 2012

ABINGDON, UNITED KINGDOM--(Marketwire -06/12/12)- SUMMIT ACHIEVES SMT C1100 PHASE 1 DOSING MILESTONE THAT TRIGGERS MILESTONE PAYMENT Summit (SUMM.L), a UK drug discovery company, today announced that it has successfully passed a milestone in the Phase 1 trial of SMT C1100 for the treatment of the fatal genetic disease Duchenne Muscular Dystrophy ('DMD'), which triggered the final payment from a $1.5 million funding agreement with US-based DMD organisations. SMT C1100, an oral small molecule compound, is a potential disease-modifying drug that works by increasing, or upregulating, the amount of a naturally occurring protein called utrophin. The Phase 1 dose-escalation study in healthy volunteers was initiated in May 2012 and will now progress to the stage where participants receive multiple doses. Results from the trial are expected by the end of this year. The Phase 1 trial is being supported by a group of US-based DMD organisations: the Muscular Dystrophy Association, Charley's Fund, Cure Duchenne, the Foundation to Eradicate Duchenne, Nash Avery Foundation and Parent Project Muscular Dystrophy. "We are grateful for the continuing support from the DMD organisations as we make significant progress in the Phase 1 trial of SMT C1100," said Glyn Edwards, Chief Executive Officer of Summit. "The funding … Continue reading

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Ditch Your Unwanted CDs, Do Autism Research a Solid

Posted: Published on June 12th, 2012

Remember us? We're CDs! CD Sweep will take those old discs off your hands for free and it's tax deductible If you're running a bit behind schedule on the whole spring cleaning thing, you can still get rid of the stacks of CDs you've been meaning to chuck, and now for a good cause: CD Sweep, an initiative benefitting the Autism Science Foundation, is looking to whisk away your old CDs because they need them more than you do. Founded last year, CD Sweep takes used CD and DVD donations to iPodmeister, a CD reseller that ships used discs to overseas countries, where they have higher resale value. Each disc donated earns 50 cents that is then donated to ASF, which provides funding directly to scientists conducting research into the causes and treatment of autism.Donating itself is probably just as easy (if not easier) than what you were planning on doing with your discs (depending on how much you hate CDs, that is): For free! So start sending them in, because, unlike the trip to the dumpster you might've been planning, donations to CD Sweep are totally tax-deductible ASF is a 501 (c)(3) public charity and because Melissa Auf der … Continue reading

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Hypertension – Hypertension and Stroke by Dr Michael D Hill, 2010 – Video

Posted: Published on June 12th, 2012

11-06-2012 23:22 Title: Recommendations for the management of hypertensive patients with STROKE (cerebrovascular disease) Objectives: ? To discuss hypertension as a risk factor for stroke ? To discuss the management of hypertension in the setting of stroke ? To outline acute treatment (072h) and chronic treatment About the speaker: Michael D. Hill, MD MSc FRCPC, Calgary Stroke Program University of Calgary About this talk: Presented at the 23rd Scientific Meeting of the International Society of Hypertension 2010, Vancouver Excerpt from: Hypertension - Hypertension and Stroke by Dr Michael D Hill, 2010 - Video … Continue reading

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Diagnosis of Stroke in New Jersey Children on the Rise

Posted: Published on June 12th, 2012

-- Advanced Medicine and Improved Awareness Contribute to Trend -- Study Published Today by Researchers at the Cardiovascular Institute of New Jersey at UMDNJ-Robert Wood Johnson Medical School Newswise New Brunswick, NJ Stroke is one of the top 10 causes of death among children according to the National Stroke Association. A new study published today shows that in New Jersey, the diagnosis of ischemic stroke in children, resulting from a loss or obstruction of blood to the brain, is on the rise. The research, published in Neurology, the medical journal of the American Academy of Neurology, was conducted by researchers at the Cardiovascular Institute of New Jersey (CVI) at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School. This is the first statewide study that examines the incidence and long-term mortality from all types of stroke in New Jersey children from one month to 19 years of age, said Sampada Gandhi, MBBS, MPH, instructor of medicine and primary author of the study. The data report on an important trend for which little evidence exists, but which is imperative for physicians to understand to improve diagnosis and treatment in children with stroke. The researchers used the Myocardial … Continue reading

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Dr. Larry Goldstein comments: Small changes in treatment keep stroke patients alive

Posted: Published on June 12th, 2012

By RON WINSLOW Stroke, until recently the third leading cause of death in the U.S., has dropped back to fourth place, reflecting a host of gradual improvements in preventing and treating the disease. The change isn't a result of major advances in new medicines or devices. Instead, medical experts cite improvements in controlling people's risk factors such as high blood pressure and smoking. They also point to the increase in recent years in the number of designated stroke centers and emergency rooms that are specially equipped for stroke patients. A recent study underlines the incremental progress being made. Researchers in California found that treating stroke patients with cholesterol-lowering drugs called statins throughout a hospital stay substantially improved survival rates and increased the chances of patients being discharged to their home instead of to a nursing home. "In the country as a whole, there has been a dramatic reduction in stroke-related mortality in the last few years," said Larry Goldstein, director of the Duke Stroke Center at Duke University Medical Center, Durham, N.C. "We're learning more and more about preventing stroke." In the 10 years ending in 2008, the latest data available, the death rate from stroke, as a percentage of … Continue reading

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