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Remarkable robot speeds stroke treatment in Clinton

Posted: Published on June 12th, 2012

Posted on: 3:00 pm, June 12, 2012, by John David, updated on: 04:05pm, June 12, 2012 Robots used to be the subject of science fiction novels and vintage movies. Now, real-life medicine is tapping into this technology to treat stroke patients. Its taking place between Mercy Medical Center in Clinton and University of Iowa Hospitals and Clinics. These are steps of gratitude for Gerri and Highland Nichols. It felt good, she said. The Clinton woman, 69, is back on her feet after suffering a stroke on May 20. With this, its just amazing that I can walk and talk, she said. A quick recovery, thanks in part to a robot. Inside the Mercy Medical Center Emergency Room, doctors from Clinton and the University of Iowa team up for a teleconference. Its just like the link that helped to treat Gerri. It is the first robot in Iowa for telemedicine, said Dr. Harold Adams, director of the University of Iowa Stroke Center. Telemedicine is in many ways the future for medicine in rural areas similar to Iowa. Iowa City doctors control a camera to see through the robot in Clinton. The stroke team runs tests and talks directly with patients. I … Continue reading

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PsychoGenics Inc. Announces Positive Efficacy Data in Levodopa Induced Dyskinesia in Parkinson’s Patients

Posted: Published on June 12th, 2012

TARRYTOWN, N.Y.--(BUSINESS WIRE)-- PsychoGenics Inc. today reported positive results from a clinical study of eltoprazine in levodopa induced dyskinesia (LID) in Parkinson's disease (PD) patients. Eltoprazine met the primary objective of the study by exhibiting a statistically significant reduction in LID at the 5 mg dose (p = 0.0007) and the 7.5 mg dose (p = 0.0467), without adversely affecting levodopa efficacy. Eltoprazine was also well tolerated in this study and there were no serious adverse events. Eltoprazine is a selective 5-HT1A/1B partial agonist. Pre-clinical data from multiple models of PD show that eltoprazine effectively reduces LID at relatively low doses. Chronic administration of eltoprazine for 45 days shows not only suppression of LID and no tolerance but also protection from development of dyskinesias. In addition, other preclinical and clinical data support the use of eltoprazine to treat the non-motor symptoms of PD such as cognitive impairment and depression. In this double-blind, randomized, placebo-controlled, dose-finding study conducted at two sites in Sweden, twenty-two patients were given single doses of eltoprazine and placebo along with a challenge dose of levodopa at each of the 5 treatment visits and assessed for parkinsonian and dyskinesia symptoms over a period of three hours post-treatment. … Continue reading

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Acorda Therapeutics to Present at Wells Fargo 2012 Healthcare Conference

Posted: Published on June 12th, 2012

HAWTHORNE, N.Y.--(BUSINESS WIRE)-- Acorda Therapeutics, Inc. (ACOR) today announced that Jane Wasman, Chief, Strategic Development and General Counsel, will present at the Wells Fargo 2012 Healthcare Conference on Tuesday, June 19, 2012 at 2:30 pm ET at the Intercontinental Hotel in Boston, MA. A live audio webcast of the presentation can be accessed under Investor Events in the Investor section of the Acorda website at http://www.acorda.com, or you may use the link: http://cc.talkpoint.com/well001/061912a_hr/?entity=31_1SEFMSO Please log in approximately 5 minutes before the scheduled time of the presentation to ensure a timely connection. An archived version of the webcast will be available until July 19, 2012 on the Investors section of http://www.acorda.com. About Acorda Therapeutics Acorda Therapeutics is a biotechnology company focused on developing therapies that restore function and improve the lives of people with MS, spinal cord injury and other neurological conditions. Acorda markets AMPYRA (dalfampridine) Extended Release Tablets, 10 mg, in the United States as a treatment to improve walking in patients with multiple sclerosis (MS). This was demonstrated by an improvement in walking speed. AMPYRA is marketed outside the United States as FAMPYRA (prolonged-release fampridine tablets) by Biogen Idec under a licensing agreement from Acorda. AMPYRA and FAMPYRA are … Continue reading

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BHR Pharma Expands SyNAPSe® Trial into Thailand, China and Russia

Posted: Published on June 12th, 2012

HERNDON, Va., June 12, 2012 /PRNewswire/ --BHR Pharma's SyNAPSe clinical trial is now enrolling patients suffering from severe traumatic brain injury (TBI) at 14 sites in Thailand, China and Russia. The trial currently has 153 participating sites (Level 1 and 2 trauma centers) worldwide. The 500th of 1,180 patients needed to complete the global Phase III, multi-center trial was enrolled at the end of May in the United States. SyNAPSe is evaluating the effectiveness of BHR-100, a proprietary intravenous progesterone infusion formulation, as a neuroprotective agent for treating severe TBI patients. The U.S. Food and Drug Administration had granted Orphan Drug designation to BHR-100 and have placed the drug on a Fast Track status designed to accelerate its potential approval. "In the past four months we've added 28 clinical trial sites, including additional centers in the United States and Europe, and we're working towards opening six Malaysian sites in the near future," said Thomas W. MacAllister, JD, PhD, President & CEO of BHR Pharma. "We're on track to complete enrollment for this pivotal clinical trial early next year, with the intent of bringing the first-ever treatment for TBI to market." TBI is a serious public health problem that affects more … Continue reading

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Some Stem-Cells May Not Be The Answer For Heart Disease

Posted: Published on June 12th, 2012

June 12, 2012 The use of stem-cells building-block cells that are harvested from embryos or adults to treat heart disease could rely on faith as much as it does science, after billions of dollars in research has not produced the results that researchers have been looking for. Questions and concerns on the topic arose during the recent opening of the multi-million-dollar Scottish Center for Regenerative Medicine (SCRM) in Edinburgh, chaired by Sir Ian Wilmut, the renowned scientist whose Dolly the sheep clone in 1996, was a groundbreaking step in stem cell technology. During the opening ceremonies of the Center, Christine Mummery of the Leiden University Medical Center in the Netherlands discussed how a 2001 claim, based on mice experimentation, indicated that bone-marrow cells could mend heart damaged by coronary disease, caused a mad rush of people to the clinics looking for a cure-all. With nothing in the way of systematic research in animals, the first patients were being treated within a year, prematurely by Mummerys account. She argued that the paper that launched the mass stampede was completely wrong, and subsequent studies proved that. But despite the findings, the 2001 paper has never been withdrawn. Norwegian professor Harald Arnesen in … Continue reading

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International Stem Cell Corporation Announces Marketing Plans for Its Wholly Owned Subsidiary Lifeline Skin Care

Posted: Published on June 12th, 2012

CARLSBAD, Calif.--(BUSINESS WIRE)-- International Stem Cell Corporation (ISCO) (www.internationalstemcell.com) has announced new sales and marketing initiatives for its Lifeline Skin Care products (www.lifelineskincare.com). These efforts are designed to enable Lifeline to robustly, strategically and profitably grow the business. Consumer Advertising During June and July, new integrated advertising campaigns will be launched in three marketing channelsonline, in newspapers and magazines, and through direct mail. The campaigns will feature Lifelines innovative stem cell technology and proof of the brands potential: younger looking skin. Although the ads will eventually be national in reach, the first few months will be devoted to optimizing the creative approach, targeting, frequency, timing, positioning, offer and ROI. Key Opinion Leader and Peer Group Influencer Elizabeth K. Hale, MD, one of the nation's top dermatologists, is now endorsing Lifeline Skin Care to both consumer and trade audiences. Dr. Hale is an Associate Clinical Professor of Dermatology at New York University, a private practitioner and a guest of the Doctor Oz show, the Today Show and Good Morning America. During the week of June 4 she met with beauty editors for Prevention, Health, Town and Country, Allure, FoxNews.com and InStyle, to present Lifeline Skin Care and its unique technology. The … Continue reading

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Life Technologies and Cellular Dynamics International Partner for Global Commercialization of Novel Stem Cell …

Posted: Published on June 12th, 2012

CARLSBAD, Calif., June 12, 2012 /PRNewswire/ -- Life Technologies Corporation (LIFE) today announced a partnership with Cellular Dynamics International (CDI), the world's largest producer of human cells derived from induced pluripotent stem (iPS) cells, to commercialize a set of three new products optimized to consistently develop and grow human iPS cells for both research and bioproduction. The partnership marries CDI's leadership in human iPS cell development with Life Technologies' expertise in stem cell research tool manufacturing and global distribution network to make these novel technologies accessible to researchers around the world. Life Technologies' commercialization of Essential 8 Medium, Vitronectin (VTN-N), and Episomal iPSC Reprogramming Vectors addresses several challenges associated with developing relevant cells for use in a wide range of studies, from basic and translational research to drug discovery efforts. The effectiveness of these products is the focus of recent validation studies published in the journals Nature Methods and PLoS One. "The launch of these new stem cell culture products furthers CDI founder and stem cell pioneer Jamie Thomson's vision to enable scientists worldwide to easily access the power of iPSC technology, thus driving breakthroughs in human health," noted Bob Palay, CDI Chief Executive Officer. To eliminate the variability introduced … Continue reading

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BGI, GE Healthcare team up on pioneering stem cell science projects

Posted: Published on June 12th, 2012

Public release date: 12-Jun-2012 [ | E-mail | Share ] Contact: Jia Liu liujia@genomics.cn BGI Shenzhen Chalfont St. Giles, UK, and Shenzhen, China 12 June, 2012 GE Healthcare, the healthcare business of GE (NYSE: GE), and BGI, the world's largest genomics organization, jointly announced today a pioneering multi-year research collaboration in stem cell science. The objective of the collaboration is to help advance the potential global utility of stem cell-derived assays for use in drug discovery and toxicity testing by exploring the underlying genetic variation between ethnically diverse human stem cell lines. The collaboration was announced at a signing ceremony attended by Dr Amr Abid, General Manager Cell Technologies, GE Healthcare Life Sciences and Lin Fang, Vice President of BGI, Ye Yin, Deputy President of BGI, and Yutao Du, Deputy President of BGI. The collaborating parties are initially undertaking two ground-breaking projects. Firstly, BGI is performing genome sequencing and epigenetic analysis on cardiomyocytes and hepatocytes supplied by GE Healthcare Life Sciences. The aim is to map out the genetic variation across an ethnically diverse range of stem cell lines and to examine the changes that occur during differentiation into specific cell types in order to increase the understanding of cell … Continue reading

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Heart disease and stem-cell treatments: caught in a clinical stampede

Posted: Published on June 12th, 2012

A few years ago, concerns over these heart trials were voiced by a Norwegian professor, Harald Arnesen. He concluded in 2007 that they are not convincing and that one German team had achieved striking results only because the control group in its trial had done particularly badly. Prof Arnesen called for a moratorium on this kind of stem-cell therapy. That still did not deter the clinicians. This January, another trial funded by the EU was announced the largest of all, with 3,000 heart-attack patients recruited from across Europe. The idea behind the trials is straightforward. During a heart attack, a clogged blood vessel starves heart muscle of oxygen. Up to a billion heart muscle cells, called cardiomyocytes, can be damaged, and the body responds by replacing them with relatively inflexible scar tissue, which can lead to fatal heart failure. So why not implant stem cells that can grow into cardiomyocytes? Stem cells, of course, come in many kinds: the embryonic variety have the potential to turn into all 200 cell types in the body. Adult stem cells, harvested from the patient, have a more limited repertoire: bone marrow stem cells generate blood cells, for example. So to claim, as was … Continue reading

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Does the Effect of Nanoparticles on Amino Acids Translate into a Risk for Consumers?

Posted: Published on June 12th, 2012

I am sure for the next few daysif not weeks and even yearsresearch out of Trinity College Dublin will be portrayed in the press and among some NGOs as "nanotechnology causes arthritis." Unfortunately, the story of the researchwhich was published in the journal Nanomedicineis a bit more complicated than that and the details will likely get lost in the furor that the initial headlines will generate. Basically, the researchers examined whether proteins when exposed to certain nanoparticles can change the amino acid arginine into the amino acid citrulline. This process known as post-translational citrullination of proteins has been linked to autoimmune diseases like rheumatoid arthritis. So maybe to avoid some confusion, it might be best to say from the outset that this research does not establish the risk of nanoparticles but only their potential hazard under very controlled (but unusual) circumstances. Further, despite what the press release may claim, I dont see how they have established much in the way of safety implications for the use and ultimate disposal of nanotechnology products and materials. Whenever I see a story about nanoparticles and toxicity, I immediately drag out my formula for understanding risk: Hazard x Exposure = Risk. When you consider … Continue reading

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