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Personalized medicine study using genetic data in EMRs signs up Air Force

Posted: Published on June 1st, 2012

As the cost of mapping out personal genomes goes down, the more potentially lifesaving but sensitive genetic data is available. Although the day when its commonplace to have that personal information in a medical record may be several years away, it is coming. And health insurers and hospitals need to think about how that information will be processed and transmitted in electronic medical records. The Air Force Medical Service is collaborating with personalized medicine research center, the Coriell Institute for Medical Research in Camden, New Jersey in a study to review and evaluate medical evidence assess, among other things, best practices for using genetic information in EMRs, according to Coriell president Dr. Michael Christman. It will look at how the data should be displayed and how it should be shared with physicians. About 2,000 active duty medical service personnel are expected to participate in the six-year Patient-Centered Precision Care Research program longitudinal study. It has already begun the recruitment process. Johns Hopkins University Applied Physics Laboratory will also offer research and program management support for the study. The institute is working on a similar study with Ohio State University Medical Center. Excerpt from: Personalized medicine study using genetic data in … Continue reading →

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29 Johns Hopkins stem cell researchers awarded funding

Posted: Published on June 1st, 2012

Public release date: 30-May-2012 [ | E-mail | Share ] Contact: Vanessa McMains vmcmain1@jhmi.edu 410-502-9410 Johns Hopkins Medical Institutions This year the Maryland Stem Cell Research Fund awarded 29 of 40 grants to Johns Hopkins researchers for the study of stem cell metabolism and regulation, the creation of new cell models for human diseases such as schizophrenia and Rett syndrome, which previously could be studied only in animals, and the development of new potential therapies. Researchers whose preliminary data promised greater discoveries were awarded Investigator-Initiated grants. Jeff Bulte, Ph.D., professor of radiology, biomedical engineering and chemical and biomolecular engineering and a member of the Institute for Cell Engineering, hopes to develop a cell therapy for treatment of type 1 diabetes an autoimmune disorder in which the immune system kills the insulin-producing cells that help regulate blood sugar. By developing cloaked stem and insulin-producing cells that can evade immune system detection, Bulte and his team hope to replace damaged cells and restore insulin levels in patients. Grants were awarded to: Several Johns Hopkins investigators were awarded Exploratory grants for researchers either new to the stem cell field or with untested but promising new ideas. Miroslaw Janowski , M.D., Ph.D., a research … Continue reading →

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Pharmacists warn against counterfeit meds sold online

Posted: Published on May 31st, 2012

QUINCY, Ill. (WGEM) --A shortage of some prescription drugs or just the cost of medicine is driving more people to the Internet. They're counting on online pharmacies to deliver the pills they need. But you may not be getting what you paid for and it could be dangerous to your health. Dixie Wallace picked up her prescription from the Hy-Vee pharmacy. Wallacesays she's comfortable knowing exactly where it came from and would never buy her pills online. "The pharmacist checks everything and double checks. I would be very skeptical of that coming from India or wherever," said Wallace. Experts say Wallace is right to be skeptical. "Pretty much any name brand medication can have a counterfeit," said Hy-Vee pharmacist Jason Tipton. Pharmacists say some of the more popular counterfeit medications are Viagra and Adderall. Drug manufacturers now use holographic seals for consumers to know the difference between what is real and fake. FDA lab tests recently found counterfeit Adderall with the wrong active ingredient, containing pain medicine instead. But some counterfeits can contain more harmful substances. Read more: Pharmacists warn against counterfeit meds sold online … Continue reading →

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DreamHost and StopBadware Combine Powers to Make the Web Safer

Posted: Published on May 31st, 2012

LOS ANGELES, CA--(Marketwire -05/31/12)- DreamHost, a global full-service web hosting company, has today announced a deep and meaningful partnership with nonprofit anti-malware organization StopBadware (www.stopbadware.org). DreamHost will contribute both funds and forensic intelligence to further StopBadware's tireless efforts to identify and help cleanse the Internet of websites distributing malware. DreamHost will also participate in, and supply color commentary to, Stop Badware's Partners Forum, an ongoing conversation among industry leaders and security experts. Members of the Partners Forum also meet on a monthly basis with the shared goal of making the Internet safer through a comprehensive combination of information sharing, group collaboration, and raw techie brainpower. Asked for comment about the arrangement, DreamHost customer Johnathan Doether offered, "I'm not the young man I used to be. I sometimes need some help in the bedroom department if you know what I mean." Pausing to deliver a creepy wink half-shrouded in unkempt gray eyebrow hair, Doether continued, "Imagine my surprise when I opened my own website one day only to discover that everything had been replaced by links to a Canadian pharmacy specializing in exactly what I was looking for. Classic glass half-full situation. All this happened because, well... I'm not exactly good … Continue reading →

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Heart-Attack-Patient-Receives-Adult-Stem-Cell-Therapy- – Video

Posted: Published on May 31st, 2012

30-05-2012 10:25 Excerpt from: Heart-Attack-Patient-Receives-Adult-Stem-Cell-Therapy- - Video … Continue reading →

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How to Use the Advanced Cell Therapy System – Video

Posted: Published on May 31st, 2012

30-05-2012 16:02 Ovation Cell Therapy Tips for Thicker, Stronger, Longer Hair. Original post: How to Use the Advanced Cell Therapy System - Video … Continue reading →

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First Success of Targeted Therapy in Most Common Genetic Subtype of Non-Small Cell Lung Cancer

Posted: Published on May 31st, 2012

ASCO Abstract 7503 Study reports first success of targeted therapy in most common genetic subtype of non-small cell lung cancer Newswise BOSTONA novel compound has become the first targeted therapy to benefit patients with the most common genetic subtype of lung cancer, an international clinical trial led by scientists at Dana-Farber Cancer Institute and other institutions will report at the annual meeting of the American Society of Clinical Oncology (ASCO) June 1-5 in Chicago. Pasi A. Jnne, MD, PhD, scientific co-director of Dana-Farbers Belfer Institute for Applied Cancer Science, will present the findings from the randomized phase II study (abstract 7503) on Monday, June 4, 3 p.m. CT, E Hall D2, McCormick Place. A video commentary by Jnne on the findings is available, youtu.be/eqTFj0Gu5Bw. The study involved 87 non-small cell lung cancer (NSCLC) patients whose tumors carry a mutation in the gene KRAS. Such tumors account for about 20 percent of NSCLC cases, but no targeted therapy has proved effective against them in previous clinical research. The drug under investigation, selumetinib, doesnt attack KRAS directly, but interferes with one of its molecular henchmen, a protein called MEK. Participants in the study all had advanced stages of the disease. They received … Continue reading →

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NeoStem to Present at Six Conferences in June

Posted: Published on May 31st, 2012

NEW YORK, May 31, 2012 (GLOBE NEWSWIRE) -- NeoStem, Inc. (NYSE Amex:NBS) ("NeoStem" or the "Company"), an international biopharmaceutical company focused on cell based therapies, announced today that Company management will present at six conferences in June. International Society for Cellular Therapy Annual Meeting National Investment Banking Association Conference International Society for Stem Cell Research 10th Annual Meeting The Biotechnology Industry Organization (BIO) International Conference Alliance for Regenerative Medicine -- Clinical Outlooks for Regenerative Medicine 2012 Marcum's Inaugural MicroCap Conference About NeoStem, Inc. NeoStem, Inc. ("NeoStem") is a leader in the development and manufacture of cell therapies. NeoStem has a strategic combination of revenues, including that which is derived from the contract manufacturing services performed by Progenitor Cell Therapy, LLC, a NeoStem company. That manufacturing base is one of the few cGMP facilities available for contracting in the burgeoning cell therapy industry, and it is the combination of PCT's core expertise in manufacturing and NeoStem's extensive research capabilities that positions the company as a leader in cell therapy development. Amorcyte, LLC, also a NeoStem company, is developing a cell therapy for the treatment of cardiovascular disease. Amorcyte's lead compound, AMR-001, represents NeoStem's most clinically advanced therapeutic and is enrolling patients … Continue reading →

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Oral Transmucosal Drug Delivery

Posted: Published on May 31st, 2012

NEW YORK, May 31, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Oral Transmucosal Drug Delivery http://www.reportlinker.com/p0870772/Oral-Transmucosal-Drug-Delivery.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology In their search for alternative delivery methods that will enhance compliance and improve safety, drug developers and researchers are discovering that the permeability of mucous membranes provides a convenient route for the systemic delivery of new and existing therapeutic drugs. Transmucosal delivery offers the potential for once daily dosing of oral drugs and avoids the effects of first pass metabolism. On the provider side, the development of alternative methods of drug administration has improved the ability of physicians to manage specific problems. Practitioners now recognize the rapid onset, relative reliability, and the general lack of patient discomfort when drugs are administered by the transmucosal route. We expect this market to experience healthy growth through 2015 as buccal technology is applied to existing drugs and as transmucosal formulations become an important route of administration for an increasing number of new NCEs. Growth in this sector will also be driven by the pressure to extend market protection for numerous existing drugs with soon-to-expire patents. Highlights Analyzes and evaluates oral transmucosal drug delivery technology platforms and their impact … Continue reading →

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'Intelligent medicine' erases side effects

Posted: Published on May 31st, 2012

Public release date: 31-May-2012 [ | E-mail | Share ] Contact: Soeren Kragh Moestrup sm@biokemi.au.dk (45) 28-99-22-82 Aarhus University Scientists at Aarhus University, Denmark in collaboration with the biotech company Cytoguide now publish a key to use glucocorticoid steroids in a kind of intelligent medicine that specifically hits the relevant cells. Data are based on rodent studies but if this principle is translated to humans it may greatly improve todays hazardous treatment with this type of potent steroids. This is the main perspective in the research now published in the recognized research journal Molecular Therapy in the Nature Publishing group. 50-fold higher potency Synthetic glucocorticoid steroid are used in many acute and chronic inflammatory diseases including many autoimmune diseases such as rheumatoid arthritis. This is the most potent anti-inflammatory medicine, but its use is hampered by serious side effects such as osteoporosis, loss in muscle mass, diabetes and immunosuppression. The new data from the scientists now show that they can target the drugs directly to he 'macrophage' immune cells. These cells play a main role in inflammation and their damaging effect on the surrounding tissues is strongly dampened by the glucocorticoid steroids. The new technology is based on the coupling … Continue reading →

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