Page 6,843«..1020..6,8426,8436,8446,845..6,8506,860..»

Research and Markets: Plasma Medicine. Applications of Low-Temperature Gas Plasmas in Medicine and Biology

Posted: Published on May 26th, 2012

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/xf5djc/plasma_medicine_a) has announced the addition of the "Plasma Medicine. Applications of Low-Temperature Gas Plasmas in Medicine and Biology" report to their offering. The introduction of low temperature plasma technology to medical research and to the healthcare arena in general is set to revolutionise the way we cure diseases. This innovative medium offers a valid and advantageous replacement of traditional chemical-based medications. Its application in the inactivation of pathogens in particular, avoids the recurrent problem of drug resistant microorganisms. This is the first book dedicated exclusively to the emerging interdisciplinary field of plasma medicine. The opening chapters discuss plasmas and plasma chemistry, the fundamentals of non-equilibrium plasmas and cell biology. The rest of the book is dedicated to current applications, illustrating a plasma-based approach to wound healing, electrosurgery, cancer treatment and even dentistry. The text provides a clear and integrated introduction to plasma technology and has been devised to answer the needs of researchers from different communities. It will appeal to graduate students and physicists, engineers, biologists, medical doctors and biochemists. Key Topics Covered: Foreword Part I. Introduction to Non-equilibrium Plasma, Cell Biology, and Contamination: 1. Introduction 2. Fundamentals of non-equilibrium plasmas 3. Non-equilibrium plasma sources … Continue reading

Posted in Cell Medicine | Comments Off on Research and Markets: Plasma Medicine. Applications of Low-Temperature Gas Plasmas in Medicine and Biology

UC San Diego researchers receive new CIRM funding

Posted: Published on May 26th, 2012

Public release date: 25-May-2012 [ | E-mail | Share ] Contact: Scott LaFee slafee@ucsd.edu 619-543-6163 University of California - San Diego Five scientists from the University of California, San Diego and its School of Medicine have been awarded almost $12 million in new grants from the California Institute for Regenerative Medicine (CIRM) to conduct stem cell-based research into regenerating spinal cord injuries, repairing gene mutations that cause amyotrophic lateral sclerosis and finding new drugs to treat heart failure and Alzheimer's disease. The awards mark the third round of funding in CIRM's Early Translational Awards program, which supports projects that are in the initial stages of identifying drugs or cell types that could become disease therapies. More than $69 million in awards were announced yesterday, including funding for first-ever collaboratively funded research projects with China and the federal government of Australia. "With these new awards, the agency now has 52 projects in 33 diseases at varying stages of working toward clinical trials," said Jonathan Thomas, JD, PhD and CIRM governing board chair. "Californians should take pride in being at the center of this worldwide research leading toward new cures. These projects represent the best of California stem cell science and the … Continue reading

Posted in Cell Medicine | Comments Off on UC San Diego researchers receive new CIRM funding

UC San Diego Scientists Net $12 Million For Stem Cell Research

Posted: Published on May 26th, 2012

Five UC San Diego scientists have received almost $12 million combined from the California Institute for Regenerative Medicine to pay for stem cell-based research, the university announced today. A team led by Lawrence Goldstein, of the Department of Cellular and Molecular Medicine and director of the UC San Diego Stem Cell Program, was given $1.8 million to continue looking for new methods to find and test possible medications for Alzheimer's disease, according to UCSD. They use reprogrammed stem cells in their work. Dr. Mark Tuszynski, professor of neurosciences and director of the Center for Neural Repair, received $4.6 million to develop more potent stem cell-based treatments for spinal cord injuries. Gene Yeo, assistant professor in the Department of Cellular and Molecular Medicine, was awarded $1.6 million to continue research into treatments for amyotrophic lateral sclerosis. His research hopes to take advantage of recent discoveries about ALS, or Lou Gehrig's disease, which center on mutations in RNA-binding proteins that cause dysfunction and death in neurons. Dr. Eric David Adler, an associate clinical professor of medicine and cardiologist, was granted $1.7 million to screen potential drugs for Danon disease, a type of inherited heart failure that frequently kills patients by their 20s. … Continue reading

Posted in Cell Medicine | Comments Off on UC San Diego Scientists Net $12 Million For Stem Cell Research

City of Hope Receives $5 Million Grant to Develop T Cell Treatment Targeting Brain Tumor Stem Cells

Posted: Published on May 26th, 2012

DUARTE, Calif.--(BUSINESS WIRE)-- City of Hope was granted a $5,217,004 early translational research award by the California Institute for Regenerative Medicine (CIRM) to support the development of a T cell-based immunotherapy that re-directs a patients own immune response against glioma stem cells. City of Hope has been awarded more than $49.7 million in grant support from CIRM since awards were first announced in 2006. City of Hope is a pioneer in T cell immunotherapy research, helping to develop genetically modified T cells as a treatment for cancer. This strategy, termed adoptive T cell therapy, focuses on redirecting a patients immune system to specifically target tumor cells, and has the potential to become a promising new approach for treatment of cancer. In this research, we are genetically engineering a central memory T cell that targets proteins expressed by glioma stem cells, said Stephen J. Forman, M.D., Francis and Kathleen McNamara Distinguished Chair in Hematology and Hematopoietic Cell Transplantation and director of the T Cell Immunotherapy Research Laboratory. Central memory T cells have the potential to establish a persistent, lifelong immunity to help prevent brain tumors from recurring. The American Cancer Society estimates that more than 22,000 people in the U.S. will … Continue reading

Posted in Cell Medicine | Comments Off on City of Hope Receives $5 Million Grant to Develop T Cell Treatment Targeting Brain Tumor Stem Cells

Cell therapy may ease chronic pain

Posted: Published on May 26th, 2012

Washington, May 25 : A new study has described how a cell therapy might one day be used not only to quell some common types of persistent and difficult-to-treat pain, but also to cure the conditions that give rise to them. UCSF scientists, working with mice, focused on treating chronic pain that arises from nerve injury -- so-called neuropathic pain. In their study, the scientists transplanted immature embryonic nerve cells that arise in the brain during development and used them to make up for a loss of function of specific neurons in the spinal cord that normally dampen pain signals. A small fraction of the transplanted cells survived and matured into functioning neurons. The cells integrated into the nerve circuitry of the spinal cord, forming synapses and signaling pathways with neighbouring neurons. As a result, pain hypersensitivity associated with nerve injury was almost completely eliminated, the researchers found, without evidence of movement disturbances that are common side effects of the currently favoured drug treatment. 'Now we are working toward the possibility of potential treatments that might eliminate the source of neuropathic pain, and that may be much more effective than drugs that aim only to treat symptomatically the pain that … Continue reading

Posted in Cell Therapy | Comments Off on Cell therapy may ease chronic pain

New Drug For Destroying Human Cancer Stem Cells

Posted: Published on May 26th, 2012

Editor's Choice Main Category: Cancer / Oncology Article Date: 25 May 2012 - 13:00 PDT Current ratings for: 'New Drug For Destroying Human Cancer Stem Cells' 3.67 (3 votes) 3 (2 votes) Mick Bhatia, lead researcher of the study and scientific director of McMaster's Stem Cell and Cancer Research Institute in the Michael G. DeGroote School of Medicine, said: "The unusual aspect of our finding is the way this human-ready drug actually kills cancer stem cells; by changing them into cells that are non-cancerous." Findings from the study could pave the way for the development of anticancer drugs in the treatment of various cancers. In addition to thioridazine, the team have identified another 12 drugs that also have good potential for the same response. The study is published in the journal CELL. Cancer stem cells were first identified in certain types of leukemia by Canadian researchers over a decade ago. Since then they have been identified in ovarian, prostate, lung, brain, breast, blood, and gastrointestinal cancer. The researchers developed an automated robotic system in order to identify different compounds of several drugs, including thioridazine. Bhatia explained: "Now we can test thousands of compounds, eventually defining a candidate drug that has … Continue reading

Posted in Drug Side Effects | Comments Off on New Drug For Destroying Human Cancer Stem Cells

EMA Seeks Stronger Pradaxa Guidance for Bleeding Side Effects

Posted: Published on May 26th, 2012

Regulators in Europe have again asked Boehringer Ingelheim, the manufacturer of the blood thinner Pradaxa, to update the drugs label with additional information regarding Pradaxa bleeding side effects. According to the European Medicines Agency (EMA), the new guidance should include more specific information on when Pradaxa must not be used, as well as advice on managing patients and reversing the anticoagulant effect if Pradaxa bleeding occurs. Pradaxa was approved in Europe in March 2008 for the prevention of venous thromboembolic events following hip or knee replacement surgery. The blood thinner recently had its European approval expanded to cover patients with non-valvular atrial fibrillation to prevent stroke and systemic embolism. According to a report from Pharma Times, the number of fatal bleeding events among Pradaxa users spiked following that expansion. The EMAs Committee for Medicinal Products for Human Use (CHMP) had concluded an earlier review of Pradaxa in November 2011, after it had been linked to 250 patient deaths. At the time, CHMP asked that label information on bleeding risks be strengthened. The Committee also advised caution when using Pradaxa, and said it should be prescribed at lower doses to older patients and those with kidney problems. On Friday, CHMP pointed … Continue reading

Posted in Drug Side Effects | Comments Off on EMA Seeks Stronger Pradaxa Guidance for Bleeding Side Effects

New Drug Kills Cancer Cells Without Toxic Effects

Posted: Published on May 26th, 2012

May 25, 2012 Connie K. Ho for RedOrbit.com A group of researchers from McMaster University have found a new drug that can kill cancer stem cells in humans while avoiding the toxic side effects of other traditional cancer treatments. Over the past 15 years, researchers have thought that stem cells were the cause of many cancers. Canadian researchers first discovered cancer stem cells in particular types of leukemia in 1997. Since then, cancer stem cells have been found in blood, breast, brain, gastrointestinal, lung, ovarian, and prostate cancer. The unusual aspect of our finding is the way this human-ready drug actually kills cancer stem cells; by changing them into cells that are non-cancerous, explained Mick Bhatia, the principal investigator for the study and scientific director of McMasters Stem Cell and Cancer Research Institute in the Michael G. DeGroote School of Medicine, in a prepared statement. The anti-psychotic drug, thioridazine, showed to have no effect on normal stem cells in the study. In the past, thioridazine had been used to treat schizophrenia. The research, published in a recent edition of the science journal CELL, describes the new method and alludes to possible development of anticancer drugs to treat different cancers. Thioridazine … Continue reading

Posted in Drug Side Effects | Comments Off on New Drug Kills Cancer Cells Without Toxic Effects

Mexico election: Drugs war in spotlight

Posted: Published on May 26th, 2012

24 May 2012 Last updated at 22:46 ET By Will Grant BBC News, Michoacan Please turn on JavaScript. Media requires JavaScript to play. Rosa Isela Caballero Garcia, the wife of a Mexican journalist missing for more than five years, says not knowing if he is dead or alive is like "physical torture" There is an area of western Mexico called Tierra Caliente. The name is a reference to the soporific and oppressive heat in the region. But in this part of the world, caliente can also mean "dangerous" as well as "hot". Unfortunately, for many residents in the state of Michoacan, "Dangerous Land" is an all-too-accurate description of their towns and villages. It was here that the government declared war on the drug cartels. In December 2006, barely a week after taking office, President Felipe Calderon ordered 6,500 troops into his home state to restore order after a surge in drug-related killings. Many had expected the army's deployment to be temporary. Fast-forward almost six years, and the soldiers are still there, fighting drug traffickers on the Pacific coast and in the mountains. In fact, there are more than ever. Follow this link: Mexico election: Drugs war in spotlight … Continue reading

Posted in Drugs | Comments Off on Mexico election: Drugs war in spotlight

Drugs worth €2m seized in two raids

Posted: Published on May 26th, 2012

irishtimes.com - Last Updated: Friday, May 25, 2012, 21:36 The Irish Times takes no responsibility for the content or availability of other websites ANNA CAOLLA and BARRY ROCHE, Southern Correspondent Four people are in custody after garda seized drugs worth an estimated 2m in separate raids in Co Donegal and Co Cork today. Cannabis plants with a value of 1.6 million were seized in a raid on an "elaborate" drug cultivation operation in Laghey, Co Donegal. Two men were arrested. Garda from Ballyshannon, Co Donegal, assisted by members of the Garda National Drugs Unit discovered an estimated 2,000 cannabis plants at the premises at Trummon, Laghey. Garda described the cannabis growing operation as "elaborate". One man in his 30's and another in his 40's were arrested at the scene and both are are being questioned at Ballyshannon Garda Station under Section 2 Criminal Justice ( Drug Trafficking) Act 1996. In Cork, garda are continuing to question a Chinese man and woman arrested in city this morning following the discovery by customs officers of an estimated 400,000 worth of drugs. The duo were arrested at a house in the Greenmount area on Corks southside by garda at around 11am after they … Continue reading

Posted in Drugs | Comments Off on Drugs worth €2m seized in two raids

Page 6,843«..1020..6,8426,8436,8446,845..6,8506,860..»