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Clot drug aids stroke recovery, researchers say

Posted: Published on May 26th, 2012

Stroke victims are more likely to make a better recovery if they are given a new clot-busting drug, Scottish researchers said. More than 3,000 patients worldwide took part in Edinburgh University's trial of the rt-PA drug, which was administered after an acute ischemic stroke. Doctors found that for every 1,000 patients treated with the drug within three hours of stroke, 80 more will survive and live without help from others than if they had not been given the drug. Professor Joanna Wardlaw, from the University of Edinburgh's Centre for Clinical Brain Sciences, said, "We have looked at data from more than 7,000 stroke patients worldwide. What we see is that the drug increases patients' longer term recovery." However, patients are also at risk of death within seven days of treatment because the drug can cause a secondary bleed in the brain. Wardlaw added, "We need to find out why some people bleed and how to reduce this to increase the effectiveness of clot busting treatment." The findings, published in The Lancet medical journal, advised that the drug was effective up to six hours after a stroke. Visit link: Clot drug aids stroke recovery, researchers say … Continue reading

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Magnesium infusions provide no benefit after bleeding stroke

Posted: Published on May 26th, 2012

The common practice of infusing magnesium sulfate into patients who have suffered a hemorrhagic (bleeding) stroke provides no discernible benefit, Dutch researchers reported Friday. The study could lead to a change in treatment for victims of such strokes, which account for about 13% of the estimated 795,000 strokes that afflict Americans each year -- and about 30% of the 133,000 stroke deaths. The rest of the strokes are caused by blood clots that impede circulation in the brain. Many survivors of hemorrhagic strokes, which occur when a blood vessel in the brain leaks blood into the organ, causing acute pressure, are left permanently impaired. The only treatments for such strokes that have proved modestly effective are calcium-channel antagonists such as nimodipine. Magnesium has been proposed as a treatment because it also acts as a calcium antagonist and because it has neuroprotective effects. Small clinical trials, however, have produced mixed results. Dr. Sanne Dorhaut Mees of the Utrecht Stroke Center in the Netherlands and her colleagues had previously performed a phase 2 trial of magnesium infusions with 283 patients in the Netherlands, half of whom received infusions of the drug and half who got infusions of saline solution as a placebo. … Continue reading

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New stroke treatment is easier, safer and faster for patients

Posted: Published on May 26th, 2012

This section displays the last 50 news articles that were published. Updated05/24/2012 05:55 PM Advancements in medical technology are making it easier for patients to recover from a stroke. The first ever stent approved specifically for the treatment of blood clots hit U.S. hospitals a month and a half ago. Upstate University Hospital was one of those early adopters. As our Katie Gibas reports, doctors say it's easier, faster and safer for patients. To view our videos, you need to enable JavaScript. Learn how. install Adobe Flash 9 or above. Install now. Then come back here and refresh the page. SYRACUSE, N.Y. -- We've all heard the symptoms. "Problems talking, weakness in the arms or legs, numbness, tingling. Those are some of the major symptoms of stroke," said Dr. Eric Deshaies, the SUNY Upstate Neurovascular Center Director. The good news for those patients is a new treatment method is making it easier, faster and safer to treat blood clots in the brain. The Solitaire FR Revascularization Device was approved for widespread use in the U.S. about a month and a half ago. The device deploys a small metal net, called a stent, into the artery where the clot is. The … Continue reading

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InVivo Therapeutics Announces Webcast for Annual Shareholders Meeting to Be Held on May 30th

Posted: Published on May 26th, 2012

CAMBRIDGE, Mass.--(BUSINESS WIRE)-- InVivo Therapeutics Holdings Corp. (OTC/BB: NVIV), a developer of groundbreaking technologies for the treatment of spinal cord injuries (SCI), today announced that the Company will be conducting a webcast of the Annual Shareholders Meeting scheduled for Wednesday, May 30, 2012 at 9:00 a.m. Eastern Daylight Time at One Broadway, 5th Floor, Cambridge, MA 02142. The webcast can be accessed by interested shareholders and other parties at http://mp163419.cdn.mediaplatform.com/163419/wc/mp/4000/11124/14575/15458/Lobby/default.htm. The meeting will also be accessible by telephone in listen-only mode. From the U.S., please dial 1-877-941-2068; from outside the U.S. please dial 1-480-629-9712. All participants should reference conference I.D. 4543212. Slides from the meeting will be available to those viewing the webcast,and a replay of the webcast including presentation slides will also be available under the Investor Relations section of the InVivo Therapeutics website within 24 hours. About InVivo Therapeutics InVivo Therapeutics Holdings Corp. is utilizing polymers as a platform technology to develop treatments to improve function in individuals paralyzed from traumatic spinal cord injuries. The company was founded in 2005 based on proprietary technology co-invented by Robert S. Langer, ScD. Professor at Massachusetts Institute of Technology, and Joseph P. Vacanti, M.D., who is affiliated with Massachusetts General Hospital. … Continue reading

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TB4 Provides Both Neuroprotection and Neurorestoration When Administered Shortly after Traumatic Brain Injury in Rat …

Posted: Published on May 26th, 2012

ROCKVILLE, Md.--(BUSINESS WIRE)-- RegeneRx Biopharmaceuticals, Inc. (OTC Bulletin Board: RGRX) (the Company or RegeneRx) reported that data showing that Thymosin beta 4 (T4) provides both neuroprotection and neurorestoration after traumatic brain injury (TBI), was published in the current (May 2012) edition of the Journal of Neurosurgery, 116:10811092. As reported in the epub edition of the journal, the aims of the study were to test if T4 treatment initiated 6 hours after traumatic brain injury in rats reduces brain damage and improves functional recovery. According to the research team, Compared with saline administration, T4 treatment initiated 6 hours postinjury significantly improved sensorimotor functional recovery and spatial learning, reduced cortical lesion volume and hippocampal cell loss, and enhanced cell proliferation and neurogenesis in the injured hippocampus. Thymosin 4 treatment initiated 6 hours postinjury provides both neuroprotection and neurorestoration after TBI, indicating that T4 has promising therapeutic potential in patients with TBI. These results are extremely encouraging and are consistent with results of T4 administration in other Central nervous system injuries, as well as in cardiovascular injury models. Moreover, the reduction of brain damage, improved motor function, and regeneration of injured brain tissue, when T4 is administered 6 hours after TBI, suggest that … Continue reading

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MS symptoms 'eased' by pregnancy

Posted: Published on May 26th, 2012

24 May 2012 Last updated at 20:02 ET Researchers are carrying out clinical trials to find out if women with a range of autoimmune diseases could be helped by hormones found in pregnancy. Women with a range of conditions, including multiple sclerosis, rheumatoid arthritis and thyroid disease report dramatic improvements in their symptoms during pregnancy. However many say their conditions return, or worsen, after childbirth. Two clinical trials are being held in France and California. Researchers want to find out whether increasing levels of progesterone or oestrogen could protect women from relapses after childbirth. The MS Society has welcomed the study but urged some caution. Chief executive Simon Gillespie said: "This is encouraging. Some of the research going on, particularly the research in France at the moment, gives a potential clue and a potential way forward on treatments but long-term use of hormones is problematic. It does cause risks. "So therefore the research needs to be done properly to identify what the benefits are and what the risks are before there can be any genuine therapeutic use." The results from the French study are due in October. Read the rest here: MS symptoms 'eased' by pregnancy … Continue reading

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LC/MS Grade Reagents have ultrapure formulation.

Posted: Published on May 26th, 2012

The volatile salts, ammonium acetate and ammonium formate are utilized in LC/MS applications to improve ionization under neutral conditions in ESI-MS, while acetic acid enhances chromatography separation under acidic conditions. These new Optima LC/MS reagents have minimal metal ion content, which limits mass adduct formation, facilitating MS interpretation. In addition, the low impurity levels, confirmed by diode array detection (LC/UV), extend column life. Purity is further enhanced by a new proprietary surface treatment applied to the HDPE bottle for acetic acid, which acts as a barrier between the bottle and acid, preventing contamination by plasticizers. Acetic acid is also available in convenient, ready to use 1mL glass ampules, ensuring the freshest additive for preparing aqueous and organic mobile phases in seconds, while safely eliminating the need to measure corrosive acids. To ensure optimum quality, product uniformity and purity, the ultrapure Optima LC/MS solvent range is manufactured in ISO 9001:2008 certified facilities. Lot-to-lot consistency and high purity across the entire Optima range, including the three new reagents, ensure consistent high standards during LC/MS applications and reproducible results with extremely low background noise. For more information on the Optima LC/MS reagents range and other Fisher Chemical products please visit http://www.acros.com or contact … Continue reading

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Canadian researcher likens controversial MS treatment to faith healing

Posted: Published on May 26th, 2012

OTTAWA A member of an expert group advising the Canadian Institutes of Health Research (CIHR) about the effectiveness of a controversial treatment for multiple sclerosis has likened it to faith healing. Dr. Barry Rubin, medical director of the Toronto General Hospital's cardiac centre, and three American co-authors draw the parallel in an article entitled "The 'Liberation Procedure' for Multiple Sclerosis: Sacrificing Science at the Altar of Consumer Demand," in the current issue of the Journal of the American College of Radiology. Rubin sits on the CIHR's Scientific Expert Working Group, a 23-member international panel created by CIHR in 2010 to monitor and analyse research into the link between MS and chronic cerebrospinal venous insufficiency (CCSVI), a term coined by Italian doctor Paolo Zamboni to describe blockages in the veins of the neck and spine. Zamboni's so-called "liberation treatment" involves opening the blocked veins by inserting a balloon, a procedure known as venous angioplasty. Health Minister Leona Aglukkaq announced last month a team of researchers has been selected to conduct a clinical trial into CCSVI in about 100 MS patients. But the article by Rubin and his three co-authors says funding trials of a procedure "that has minimal basis in rational, … Continue reading

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Prayer for Mercy: Henderson family seeks a cure for 6-year-old's unique condition

Posted: Published on May 26th, 2012

Leila Navidi Mercy Doyle, 6, visits with Tina Lindquist, the program director at Brain Balance Achievement Centers in Henderson on Wednesday, May 23, 2012. Doyle has been diagnosed with the rare neurological disorder Opsoclonus MyoclonusSyndrome. By Conor Shine (contact) Thursday, May 24, 2012 | 2 a.m. Six-year-old Mercy Doyle is like a lot of girls her age. She loves coloring, swimming and The Little Mermaid. She looks up to her big sister and finds her younger brother kind of annoying. But to doctors in Nevada and around the country, Mercy is a medical mystery, a child with a unique set of symptoms theyve never seen before. Mercys medical odyssey began seemingly overnight, her parents say, four years ago during a family vacation to the beach in California. She kept falling in the sand. She couldnt run around. She was shaky. It was weird, said her father, Kevin Doyle, a worship pastor at Green Valley Christian Center. Her family rushed back home to Henderson, where Mercy was diagnosed with a viral infection that was attacking her brain. After a few months, her condition seemed to be improving. Then her symptoms worsened again. Follow this link: Prayer for Mercy: Henderson family seeks … Continue reading

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State awards stem cell grants to medical researchers

Posted: Published on May 26th, 2012

SACRAMENTO California's stem cell agency today approved two grants to UC Davis Health System researchers for their innovative work in regenerative medicine. Kyriacos A. Athanasiou, distinguished professor of orthopaedic surgery and professor and chair of biomedical engineering, and the Child Family Professor of Engineering at UC Davis, is investigating the use of skin-derived stem cells to heal cartilage injuries and debilitating conditions of the knee such as osteoarthritis. W. Douglas Boyd, professor of surgery, plans to further refine a novel approach to treating cardiovascular injuries suffered during a heart attack by using stem cells and a tissue-like scaffold to repair cardiac damage. The pair received individual grants totaling approximately $6.6 million from the California Institute for Regenerative Medicine's (CIRM) governing board. Athanasiou's and Boyd's multi-year grants were among the proposals submitted to CIRM for its third round of Early Translational Awards, which are intended to enable clinical therapies to be developed more rapidly. "Both of these scientists are conducting exciting research that could have far-reaching implications in health care," said Jan Nolta, director of the UC Davis Institute for Regenerative Cures and the university's stem cell program director. "Dr. Athanasiou is bioengineering new cartilage that could have the same physiological … Continue reading

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