Parkinson’s Disease Forecast and Market Analysis to 2035 – Market is Dominated by Generics – GlobeNewswire (press release)

May 30, 2017 04:33 ET | Source: Research and Markets

Dublin, May 30, 2017 (GLOBE NEWSWIRE) -- Research and Markets has announced the addition of the "Parkinson's Disease Forecast and Market Analysis to 2035" report to their offering.

Sizable pipeline characterized by both high growth and attrition

Parkinson's disease is a chronic and progressive neurodegenerative disorder characterized by tremors, rigidity, bradykinesia (slowness of movement), and postural instability. Patients also experience significant non-motor symptoms including changes in cognition and mood, sleep disturbances, and autonomic dysfunction. The condition is caused by the degeneration of dopamine-producing cells of the substantia nigra. Parkinson's disease is incurable, but non-fatal, resulting in poor quality of life and increasing disability as the disease progresses. Studies classify Parkinson's disease as the second most common neurologic disease following Alzheimer's disease, and it is expected to cause an increasing social and economic burden as populations age. Recent events and opinion

Parkinson's disease is predominantly treated with longstanding and mature therapies such as levodopa and the dopamine agonists, pramipexole and ropinirole. The market is therefore dominated by generics, with Teva's Azilect (rasagiline) being the last lucrative drug indicated for all Parkinson's disease patients.

Drug developers have responded by introducing new treatment options with clearly defined positions in the market, typically as an option for reducing motor fluctuations alongside levodopa therapy.

The Parkinson's disease pipeline is characterized by a high level of both growth and attrition. The vast majority of Parkinson's disease pipeline candidates are in the preclinical stages of development, however, many programs fail to progress into later stages.

Future clinical trials should aim to target a defined patient population. Clinical trials face difficulties including a high placebo response and poor recruitment of patients. The long duration and slow progressive course of the disease are key factors resulting in clinical trials requiring an extensive amount of resources.

Key Topics Covered:

1. FORECAST: PARKINSON'S DISEASE Executive Summary Market Overview and Trends Market Definition and Methodology Azilect (rasagiline) CVT-301 Duopa (levodopa/carbidopa) Neupro (rotigotine) Nouriast (istradefylline) Rytary (carbidopa/levodopa) Stalevo (carbidopa/levodopa/entacapone) tozadenant Xadago (safinamide) Primary Research Methodology

2. TREATMENT: PARKINSON'S DISEASE Primary Research Methodology Disease Definition and Diagnosis Patient Segmentation Current Treatment Options Prescribing Trends Unmet Needs in Parkinson's Disease

3. EPIDEMIOLOGY: PARKINSON'S DISEASE Executive Summary Disease Background Sources and Methodology Forecast Epidemiologist Insight Strengths and Limitations

4. MARKETED DRUGS: PARKINSON'S DISEASE Executive Summary Product Overview Product profile: Apokyn Product profile: Azilect Product profile: Duopa Product profile: Mirapex ER Product profile: Neupro Product profile: Nouriast Product profile: Ongentys Product profile: Rytary Product profile: Stalevo Product profile: Xadago

5. PIPELINE: PARKINSON'S DISEASE Executive Summary Clinical Pipeline Overview Product profile (late stage): APL-130277 Product profile (late stage): CVT-301 Product profile (late stage): ND0612 Product profile (late stage): Nurelin Product profile (late stage): tozadenant

6. APPENDIX

For more information about this report visit http://www.researchandmarkets.com/research/b86ww8/parkinsons

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Parkinson's Disease Forecast and Market Analysis to 2035 - Market is Dominated by Generics - GlobeNewswire (press release)