Prochymal Adult Human Mesenchymal Stem Cells for Treatment …

Human mesenchymal stem cells (MSCs), derived from healthy adult volunteer human donors, can be obtained from bone marrow donation and cultured in the laboratory. MSCs have shown the ability to find injured tissue, reduce and control inflammation, and assist in tissue repair.

Prochymal MSCs will be infused into patients with moderate-to-severe Crohn's disease. Infusions will occur on two separate days, 7-10 days apart. Patients will be monitored for reduced Crohn's disease symptoms.

High dose (8 million cells per kg of body weight)

Cells in plasmalyte and containing dimethylsulfoxide

Other Name: PROCHYMAL

two infusions, one week apart, each comprising adult human mesenchymal stem cells

Other Name: PROCHYMAL

Low dose: 2 million cells per kg body weight

Cells in plasmalyte and containing dimethylsulfoxide

Other Name: PROCHYMAL

two infusions, one week apart, each comprising adult human mesenchymal stem cells

Other Name: PROCHYMAL

Human mesenchymal stem cells (MSCs), derived from healthy adult volunteer human donors, can be obtained from bone marrow donation and cultured in the laboratory. MSCs have shown the ability to find injured tissue, reduce and control inflammation, and assist in tissue repair.

Prochymal MSCs will be infused into patients with moderate-to-severe Crohn's disease. Infusions will occur on two separate days, 7-10 days apart. Patients will be monitored for reduced Crohn's disease symptoms. Patients will receive high or low dose. Study is open label.

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Prochymal Adult Human Mesenchymal Stem Cells for Treatment ...