Researchers explore 3-D microsurgical anatomy of brainstem

PUBLIC RELEASE DATE:

1-Dec-2014

Contact: Connie Hughes Connie.Hughes@wolterskluwer.com 646-674-6348 Wolters Kluwer Health @WKHealth

December 1, 2014 - A study using intricate fiber dissection techniques provides new insights into the deep anatomy of the human brainstem--and helps to define "safe entry zones" for neurosurgeons performing brainstem surgery, according to a special article published in Operative Neurosurgery, a quarterly supplement to Neurosurgery, official journal of the Congress of Neurological Surgeons. These publications are published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

Neurosurgeons Dr. Kaan Yagmurlu and Dr. Albert L. Rhoton, Jr, of University of Florida, Gainesville, and colleagues performed fiber tract dissections, along with three-dimensional photography, to explore and document the complex anatomy of the brainstem. "We hope that the use of this knowledge will make surgical entry into the brainstem more accurate and safe," Dr. Rhoton and coauthors write.

Fiber Tract Dissections Guide Safe Routes for Brainstem Surgery

Working under the operating microscope, the researchers performed meticulous dissections of human brainstem specimens. They used a technique called fiber tract dissection, which traces the complex course of the nerve fibers that make up the brainstem. At each step of the dissection, 3-D photographs were obtained. In some areas, a magnetic resonance imaging technique called diffusion tensor imaging was used to help in visualizing the nerve fiber tracts.

The lowermost portion of the brain is directly connected to the spinal cord. The brainstem is involved in regulating some of the body's most basic functions. In addition to mapping and illustrating the inner anatomy of the brainstem, the researchers sought to identify the best surgical approaches to specific brainstem areas.

In their article, Drs. Yagmurlu and Rhoton and colleagues present richly detailed descriptions and 3-D images of the fiber tract anatomy of the brainstem. They also propose a short list of "safe entry zones" for each of the three major portions of the brainstem: the midbrain, pons, and medulla.

For each area, the suggested routes include key anatomical landmarks for the neurosurgeon to follow. The fundamental principle is to pass through as little normal tissue as possible, while avoiding critical areas and tracts.

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Researchers explore 3-D microsurgical anatomy of brainstem