Top Japan lab dismisses controversial stem cell study

The revelations come a week after a young researcher at the center of the scandal, which has rocked the country's scientific establishment, said she will resign after failing to reproduce the study's results

FABRICATED. In this file photo, Riken Institute investigation committee chief Shunsuke Ishi (L) explains an interim investigation report with photo datas at the institute during a news conference in Tokyo, Japan, March 14, 2014. Kimimasa Mayama/EPA

TOKYO, Japan Japan's top research institute on Friday, December 26, hammered the final nail in the coffin of what was once billed as a ground-breaking stem cell study, dismissing it as flawed and saying the work could have been fabricated.

The revelations come a week after a young researcher at the center of the scandal, which has rocked the country's scientific establishment, said she would resign after failing to reproduce the successful conversion of an adult cell into a stem cell-like state, known as "STAP" cells.

The failure marked a stunning fall from grace for 31-year-old Haruko Obokata, whose co-researcher committed suicide amid the embarrassing scandal that prompted respected science journal Nature to retract an article detailing the research.

On Friday the government-backed Riken institute, which sponsored the study, said embryonic stem cells had been added in the process of the research, hammering Obokata's contention that she had found an easier way to generate new stem cells in the lab.

"But we can't conclude whether the mixing was done on purpose or by mistake nor can we conclude who did it," probe team chief Isao Katsura, head of the National Institute of Genetics, told a news briefing in Tokyo.

In January, Riken trumpeted Obokata's simple method to re-program adult cells to work like stem cells.

The study was top news in Japan, where the photogenic Obokata, a Harvard-trained scientist, became a phenomenon.

But media attention soon grew into skepticism as doubts emerged about Obokata's papers on Stimulus-Triggered Acquisition of Pluripotency (STAP).

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Top Japan lab dismisses controversial stem cell study