Where Grey's Anatomy Left Off, and What's Ahead in Season 11 (Hint: Lots of Drama, Natch)

Ellen Pompeo and Patrick Dempsey

Grey's Anatomykicks off its 11th season in a new time slot! on Thursday, so what's in store for the docs at Grey Sloan Memorial?

Answer: Plenty of drama both at home and at work. Would you expect anything less?! We know that Meredith (Ellen Pompeo) and Derek (Patrick Dempsey) will deal with their fair share of ups and downs as he mulls a move to Washington, D.C., and that Callie (Sara Ramirez) and Arizona (Jessica Capshaw) may find themselves on the rocks again as they deal with trying to have a baby through a surrogate.

Quiz: How well do you knowGrey's Anatomy?

It remains to be seen how acutely the absence of Cristina Yang (Sandra Oh) will be felt, both by the characters and the show's viewers, but some new faces are also coming into the mix.Kelly McCrearyandCatarina Scorsonehave both been promoted to series regulars as Dr. Maggie Pierce (Meredith's sister/Richard's daughter) and Dr. Amelia Shepherd (Derek's sister/Owen's new love interest??), respectively.

Click here for a refresher on where we left off with the hospital staff, plus teasers from series creatorShonda Rhimesabout what's ahead.

What are you looking forward to in Season 11,Grey'sfans? Sound off in the comments!

Grey's Anatomy premieres Thursday at 8/7c on ABC.

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Where Grey's Anatomy Left Off, and What's Ahead in Season 11 (Hint: Lots of Drama, Natch)